963 research outputs found

    Arts: Fiction and Fiction Writers: The Americas

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    This essay by Rachel Norman, which originally appeared in the Encyclopedia of Women & Islamic Cultures, discusses contemporary Muslim fiction published in the United States with a particular focus on three novels: Mojha Kahf\u27s The Girl in the Tangerine Scarf, Laila Halaby\u27s Once in a Promised Land, and Randa Jarrar\u27s A Map of Home

    A Bastard Jargon”: Language Politics and Identity in \u3cem\u3eThe Brief Wondrous Life of Oscar Wao\u3c/em\u3e

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    This essay explores Junot Díaz\u27s only full-length novel, The Brief Wondrous Life of Oscar Wao, through the theoretical lens of sociolinguistics and examines the ways in which Díaz has attempted to overcome the publishing industry\u27s complicity in maintaining the nation\u27s ethnocentric expectations in regards to English as the only acceptable language of publication. By introducing the work of several sociolinguists into the discussion, examining the use of African American Vernacular and “nerdish” alongside the Spanish, and reviewing Díaz’s relationship with his editors, I provide a more nuanced reading of the ubiquitous code-switching throughout Oscar Wao and suggest that beyond creating a simplistic insider-outsider binary, layers of meaning are created for each individual reader

    Monitoring Global Water and Sanitation

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    The process of determining outputs and outcomes plays a key role in the setting of global targets, in defining national sector policy and strategic plans and in ensuring a continuous, safe supply of affordable water. Each of these actions, are integrally linked by aggregated data sets generated through an effective monitoring and evaluation (M&E) process. This thesis examines the various components of M&E across three case studies: Global, Kenya and Uganda, including aspects such as whether roles and responsibilities are realistically assigned and whether there is a recurring set of core indicators being monitored and reported. The research has also sought to establish an evidence base of the associated costs and efficacy of use of M&E. Through purposive and snowball sampling, fieldwork was undertaken across the case studies with 85 key stakeholders. Programme, national and global level data sets were collected through structured literature reviews, document and data archive reviews, key informant and semi-structured interviews. Qualitative and quantitative data analysis methods were applied. The results demonstrate that despite having a recurring global goal and associated target, the number and variety of indicators reported against has grown over time and at each level. In turn this is placing a burden on already resource constrained countries. Regardless of the various principles of harmonization and alignment, countries are still required to manage internally and externally driven parallel systems. Whilst the research suggests the costs of M&E are escalating, the full extent of this increase remains unknown as does the extent of efficacy of use of M&E. Despite evidence that country-led M&E processes are at some level achieving their objectives, with the continuing complexities of the sector particularly around the accompanying aid architecture, M&E is not currently ‘fit for purpose’ for use in the WASH sector and is unlikely to be providing value for money

    Food security and why Christmas dinner is in peril

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    First paragraph: The Victorians introduced many of the traditions we now associate with the festive season. Along with Christmas cards, crackers, mince pies and Santa Claus himself, they are responsible for the modern day Christmas dinner. While British households would once have had goose or beef at the centre of the table, by the end of the 19th century most were eating turkey. Access this article on The Conversation website: https://theconversation.com/food-security-and-why-christmas-dinner-is-in-peril-7068

    Food security looks very different depending on where you are sitting

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    First paragraph: In 1974, the World Food Conference declared that: “Every man, woman and child has the inalienable right to be free from hunger and malnutrition in order to develop their physical and mental faculties.” The conference set as its goal the eradication of hunger, food insecurity and malnutrition within a decade

    Incorporation of nickel into synthetic goethites and the stabilisation of mineral precursor phases - implications for natural systems

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    Over 70% of the Earth s economically recoverable nickel (Ni) resides in laterite ore deposits, however they account for less than half of the current global nickel production. During laterization, nickel and other soluble ions are taken into solution before re-precipitating within iron oxide minerals in the limonite zone, or as serpentines and other phyllosilicates in the layers below this zone. It is these laterite deposits that show the greatest potential for low energy, environmentally conscious processing. The major host of nickel in the limonite zone is the iron-oxyhydroxide mineral goethite, α-FeOOH, where up to 4 mol% Ni has been reported in natural specimens, and even higher levels in synthetic samples (5.5 mol%). The Ni is assumed to be incorporated in the crystal structure of the goethite, but previous characterisation work only demonstrated a weak to moderate correlation of mineral structure change with the nickel content in goethite. Mining companies working on the extraction and recovery of nickel from the limonite zone of lateritic deposits have noticed that the ease with which nickel can be extracted varies greatly; goethite rich ores that appear to have similar mineralogies/geologies can display extreme variation in their leachability. It is not clear why the ores behave in this way, but in order for extraction techniques and subsequent recovery of nickel to be improved, the reasons behind this variability need to be understood. The lateritic ore materials from which nickel is extracted are generally made up of a number of different mineral phases. The multiphase nature of the samples means that characterisation of the goethite-type phases from these materials is challenging. To simplify the system and allow the association of Ni into goethite and/or other iron oxyhydroxide phases to be studied in a controlled environment, a synthetic study was carried out. Ni-bearing goethites have been synthesised at a series of different temperatures and characterised by a range of analytical techniques including PXRD, IR, Raman, TGA, ICP-OES, SEM and TEM. It was found that a second phase, ferrihydrite, co-existed with the goethites, the proportion of which increased at lower synthesis temperatures and with increasing amounts of Ni. Ferrihydrite is known to be a precursor phase in the formation of goethite, but its poorly crystalline nature makes it difficult to identify using standard characterisation techniques such as PXRD. The introduction of Ni to the system increases the stability of the ferrihydrite phase, inhibiting its transformation to goethite. It is believed that some of the Ni thought to be incorporated into goethite could actually reside in an undetected ferrihydrite phase, which could account for the differences observed in the leachability of natural materials. Characterisation techniques were investigated to try and determine a simple way to identify ferrihydrite in these systems, which could ideally be used in the field to identify the presence of ferrihydrite in goethite rich ore materials. Thermal analysis proved to be particularly promising as a technique which could be used to identify ferrihydrite rich deposits before extraction, enabling the most efficient and environmentally conscious metal recovery process for each deposit to be identified. In order to investigate the way in which Ni partitions itself between structural incorporation into goethite and association with a secondary ferrihydrite phase, a new washing technique was developed using EDTA, which is capable of selectively removing the ferrihydrite phase whilst leaving the goethite intact. This investigation suggests that a maximum of ~2.5 mol% of Ni is structurally incorporated into goethite, regardless of how much is added during the synthesis. Any excess nickel, above that which is substituted into the goethite structure, was found to be associated with the poorly crystalline ferrihydrite phase. Despite being considered a metastable phase, the increased stability of ferrihydrite resulting from the presence of Ni suggests that it may persist in laterite deposits within geological systems. If ferrihydrite is indeed present in nickeliferous laterites, it may be a significant host for Ni, and potentially many other critical elements. Based on the methodology developed whilst studying synthetic samples, a characterisation program for materials from lateritic ore deposits was conducted to investigate the presence of ferrihydrite in natural systems. From the research presented and discussed in this thesis, proof of the presence or absence of ferrihydrite in laterite systems, causing variations in the leachability of the ore materials, could not be conclusively established. The thermal analysis technique developed here successfully identified and quantified ferrihydrite in the presence of goethite in synthetic systems, and showed great potential when used to characterise the lateritic goethite samples, certainly suggesting that ferrihydrite could be present in these natural ore materials. With further refinement of the methodology, to enable a larger range of sample types to be accurately analysed, TGA is a technique which could be used as a screening tool for laterite ores

    Environmental forcing, invasion and control of ecological and epidemiological systems

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    Destabilising a biological system through periodic or stochastic forcing can lead to significant changes in system behaviour. Forcing can bring about coexistence when previously there was exclusion, it can excite massive system response through resonance, it can offset the negative effect of apparent competition and it can change the conditions under which the system can be invaded. Our main focus is on the invasion properties of continuous time models under periodic forcing. We show that invasion is highly sensitive to the strength, period, phase, shape and configuration of the forcing components. This complexity can be of great advantage if some of the forcing components are anthropogenic in origin. They can be turned into instruments of control to achieve specific objectives in ecology and disease management, for example. Culling, vaccination and resource regulation are considered. A general analysis is presented, based on the leading Lyapunov exponent criterion for invasion. For unstructured invaders a formula for this exponent can typically be written down from the model equations. Whether forcing hinders or encourages invasion depends on two factors: The covariances between invader parameters and resident populations and the shifts in average resident population levels brought about by the forcing. The invasion dynamics of a structured invader are much more complicated but an analytic solution can be obtained in quadratic approximation for moderate forcing strength. The general theory is illustrated by a range of models drawn from ecology and epidemiology. The relationship between periodic and stochastic forcing is also considered

    Systematic review of SGLT2 receptor inhibitors in dual or triple therapy in type 2 diabetes

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    Background Despite the number of medications for type 2 diabetes, many people with the condition do not achieve good glycaemic control. Some existing glucose-lowering agents have adverse effects such as weight gain or hypoglycaemia. Type 2 diabetes tends to be a progressive disease, and most patients require treatment with combinations of glucose-lowering agents. The sodium glucose co-transporter 2 (SGLT2) receptor inhibitors are a new class of glucose-lowering agents. Objective To assess the clinical effectiveness and safety of the SGLT2 receptor inhibitors in dual or triple therapy in type 2 diabetes. Data sources MEDLINE, Embase, Cochrane Library (all sections); Science Citation Index; trial registries; conference abstracts; drug regulatory authorities; bibliographies of retrieved papers. Inclusion criteria Randomised controlled trials of SGLT2 receptor inhibitors compared with placebo or active comparator in type 2 diabetes in dual or combination therapy. Methods Systematic review. Quality assessment used the Cochrane risk of bias score. Results Seven trials, published in full, assessed dapagliflozin and one assessed canagliflozin. Trial quality appeared good. Dapagliflozin 10 mg reduced HbA1c by −0.54% (weighted mean differences (WMD), 95% CI −0.67 to −0.40) compared to placebo, but there was no difference compared to glipizide. Canagliflozin reduced HbA1c slightly more than sitagliptin (up to −0.21% vs sitagliptin). Both dapagliflozin and canagliflozin led to weight loss (dapagliflozin WMD −1.81 kg (95% CI −2.04 to −1.57), canagliflozin up to −2.3 kg compared to placebo). Limitations Long-term trial extensions suggested that effects were maintained over time. Data on canagliflozin are currently available from only one paper. Costs of the drugs are not known so cost-effectiveness cannot be assessed. More data on safety are needed, with the Food and Drug Administration having concerns about breast and bladder cancers. Conclusions Dapagliflozin appears effective in reducing HbA1c and weight in type 2 diabetes, although more safety data are needed

    Fifty years of monitoring and evaluation - from before Drawers of water to beyond the MDGs

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    Whether we benchmark, assess or monitor against a set of indices, indicators or selection criteria and whether we use a framework, matrix or personal judgement, everyday life is enveloped by the compelling need for measurement and accountability. This paper provides a synopsis of the evolution of the monitoring landscape existing within the WASH sector. The aim of the paper is to reflect and provoke discussion and debate on the complex, dispersed and multi-system environment that has been created over the years. It does not however, quantify the level and changing use of each of the approaches, applications or selection criteria available around the world today. Neither does it quantify or qualify the impact. However, concluding questions of whether the “pendulum has swung too far” and “is there a need for simplification and some level of standardisation” remain paramount

    From Individuals to Populations: A Symbolic Process Algebra Approach to Epidemiology

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    Is it possible to symbolically express and analyse an individual-based model of disease spread, including realistic population dynamics? This problem is addressed through the use of process algebra and a novel method for transforming process algebra into Mean Field Equations. A number of stochastic models of population growth are presented, exploring different representations based on alternative views of individual behaviour. The overall population dynamics in terms of mean field equations are derived using a formal and rigorous rewriting based method. These equations are easily compared with the traditionally used deterministic Ordinary Differential Equation models and allow evaluation of those ODE models, challenging their assumptions about system dynamics. The utility of our approach for epidemiology is confirmed by constructing a model combining population growth with disease spread and fitting it to data on HIV in the UK population
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